Pigmented nevus

Pigmented Nevus (Nevus), also known as Nevus cell Nevus, melanocyte mole, is caused by the pigment Nevus cell hyperplasia and produce of the skin, mucous membrane of benign disease characterized by color change.Pigmented nevus for a long time to maintain a stable state, recurrence after resection;But be aware there are few malignant pigmented nevus.

Medicine name: pigmented nevus

The English nameSaid Nevus

Subordinate departments: surgery - skin

Risk: the skin, mucous membrane

The main symptoms: skin or mucous membrane limitations color change

The main cause: unknown etiology

Contagious: without infectivity

Whether into the health care: it is

Introduction of disease

Pigmented nevus and pigment spots, collectively known as against pigment, belongs to the limitations of pigment abnormal lesions.Pigment spots, also known as non cell pigment against, for the skin pigment calm, no tumor cells, such as freckles, age spots, etc.Unlike pigment spots, pigmented nevus for nevus cell hyperplasia, therefore, also known as cell against.In clinic, pigment spots and pigment nevus difficult to separate.Pigment nevus cell nevus is composed of neural crest development of precursor cells, and this can produce pigment nevus cells.Pigmented nevus is a benign disease, its long time to maintain a stable state, enough, is very rare.Pigmented nevus happens to the face and neck skin, I also found in the oral mucosa.

Classification of diseases

(1) the intradermal nevus: the most common.Occurs in facial skin and hair, size is differ, the head can be up to a few centimeters, even affects half side of the neck.Uplift skin, hairy, light brown or light black, boundaries clear.By the little mole of cells.Nevus cell nests under the epithelium in the connective tissue (i.e., is located in the dermis).Normal on nevus cell nests on the surface of the cortex.Generally does not arise.

(2) boundary mole: by intradermal nevus evolved, may also occur alone.Can happen at any age, but see more with infants and young children.Lesions show flat, dark brown or dark blue, boundary can be clear.Generally small, many within a few millimeters.The surface smooth and glabrous.Can stay unchanged for a long time, a few can regress, easily enough.Consists of big nevus cell nevus cell half the nest in the bottom layer of skin, the other half in the epithelium of the shallow layer of connective tissue, the leather in the shallow.May become cancerous.

(3) compound nevus: children see more, most of lesions micro highlight the surface of the skin and a few change a papilloma samples, usually glabrous, but along with the age growth, size, color is darker.Compound nevus of boundary mole malignant change can happen.Pathology characteristic is in the process of nevus cells into dermis, often at the same time the intradermal nevus and residual border mole, for intradermal nevus and mixed form of border nevus.

Clinical manifestations of

Good hair group

Pigmented nevus can occur at any age, mostly in the day after tomorrow.

Disease symptoms

Pigmented nevus asymptomatic, such as symptomatic, be aware whether malignant.Show is black, brown or blue spots or patches, flat or slightly uplift;There are a few is a colorless pigmented nevus.

disease

Few pigment nevus malignant change happens, become a malignant melanoma.Reports about 50% of malignant melanoma is the result of pigmented nevus.Pigmented nevus in a relatively short period of time with symptoms, and color quality of a material change, must be vigilant and surgery as soon as possible.Clinical changes, the following message is pigmented nevus possible rate: (1) pain, itching;(2) the size or a small mole "satellite" around;(3) the color change, shades;(4) with inflammatory glow around;(5) induration or decay of pigmented nevus.

To identify disease

Early malignant melanoma: malignant melanoma of the skin as the skin pigment nevus, evil change occurs, the original rapid enlargement of pigmented nevus, itching, ulcers and even burst bleeding, pigment, in black or dark brown, edge become irregular, pathological changes around the satellite nodules of hemoglobin.Mucosa malignant melanoma in blue-black, or colorless (no pigment malignant melanoma), pathological changes fast growth, easy appear ulcer, often with bleeding.

Disease treatment

The vast majority of pigmented nevus needs no treatment.When facial nevus affect beautiful can be removed surgically.Can divide second resection, while larger area can also be a resection after free skin graft or adjacent skin flap transfer.Such as suspected malignant mole, surgery should be adopted a total excision biopsy;Surgery should be done on the mole boundary outside of the normal skin incision.If after excision of a small mole, stripped skin and flange can sneak direct suture.

The prognosis of disease

No recurrence after surgical resection